KAT3B (also known as EP300) encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein that functions as a histone acetyltransferase. KAT3B regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. KAT3B binding is a highly accurate process and can be used for identifying enhancers and their associated activities (1). KAT3B is also useful in the study of the role of tissue-specific enhancers in human biology and diseases on a genome wide scale. Defects in KAT3B gene are a cause of Rubinstein-Taybi syndrome that play a important role in epithelial cancer and act as a classic tumor suppressor gene (2). KAT3B Protein is ideal for investigators involved in Signaling Proteins, Acetyl/Methytransferase Proteins, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Cell Cycle, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Metabolic Disorder, Neurobiology, NfkB Pathway, and PKA/PKC Pathway research.
序列
该【干冰】KAT3B (EP300) recombinant protein-GST fusion protein - 009-001-S27S的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】KAT3B (EP300) recombinant protein-GST fusion protein - 009-001-S27S的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】KAT3B (EP300) recombinant protein-GST fusion protein - 009-001-S27S的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.