PAK2 proteins is a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell (1). The CDC42 and RAC1 induce autophosphorylation of PAK2, which stimulates sustained phosphorylation of other substrates (2). PAK2 Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Cancer, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Neurobiology, and Ser/Thr Kinases research.
序列
该【干冰】PAK2 recombinant protein-GST fusion protein - 009-001-S78的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】PAK2 recombinant protein-GST fusion protein - 009-001-S78的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】PAK2 recombinant protein-GST fusion protein - 009-001-S78的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.