TRDMT1 is responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. TRDMT1 also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, TRDMT1 is distinct and highly conserved in its function among various species. The indirect sequence recognition is also a feature of eukaryotic DNA methyltransferases, which may have arisen from a DNMT2-like RNA methyltransferase (1). DNMT2 is involved in retrotransposon silencing and telomere integrity in somatic cells (2). TRDMT1 Protein is ideal for investigators involved in Signaling Proteins, Acetyl/Methyltransferase Proteins, Apoptosis/Autophagy, Cancer, Cell Cycle, and Neurobiology research.
序列
该【干冰】TRDMT1 (DNMT2) recombinant protein-GST fusion protein - 009-001-U19的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】TRDMT1 (DNMT2) recombinant protein-GST fusion protein - 009-001-U19的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】TRDMT1 (DNMT2) recombinant protein-GST fusion protein - 009-001-U19的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.