抗人CD16纯化的抗体，不含叠氮化物-Anti-Hu CD16 Purified Azide Free代理/参数/厂家-二抗-开云·官方站线上登录平台入口

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二抗

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背景资料: CD16 (FcgammaRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgammaRIII is expressed in two forms – FcgammaRIII-A and -B. FcgammaRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgammaRIII-A is associated, moreover, with FcepsilonRI-beta subunit. Besides IgG, FcgammaRIII-A can be triggered also by oligomeric IgE. FcgammaRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.

反应性: The antibody MEM-115 recognizes an extracellular epitope in the D1 domain of CD4 antigen, a 55 kDa transmebrane glycoprotein expressed on a subset of T lymphocytes (“helper“ T cells) and also on monocytes, tissue macrophages and granulocytes. It is negative in Western blotting even with non-reduced samples of cell lysates.

其他: EXBIO是捷克一家著名的生物试剂公司，专注于流式细胞术配套试剂的开发。自1990年成立以来，EXBIO公司研发和制造的抗体分销全球。目前，EXBIO可提供超过4000种质优、价廉的研究和临床应用抗体，涵盖了血液学，免疫学，癌症，干细胞和细胞生物学等领域，如：CD分子、细胞粘附分子、细胞骨架、凋亡、细胞信号传导、肿瘤标志物、人血型、HLA、生殖等研究用抗体，涉及荧光染料如FITC、PE、PE-Cy5、PE-Cy7、APC、PerCP、PerCP-Cy5.5、Pacific Blue、Pacific Orange、Alexa Fluor 488、Alexa Fluor 647、Alexa Fluor 700、Biotin等多达13种，满足客户各类实验需求。