【干冰】Anti-Glial Fibrillary Acidic Protein (GFAP) (Rabbit) Antibody - 100-401-D60-【干冰】Anti-Glial Fibrillary Acidic Protein (GFAP) (Rabbit) Antibody - 100-401-D60代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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中文名称: 【干冰】Anti-Glial Fibrillary Acidic Protein (GFAP) (Rabbit) Antibody - 100-401-D60

英文名字: 【干冰】Anti-Glial Fibrillary Acidic Protein (GFAP) (Rabbit) Antibody - 100-401-D60

背景资料: Glial Fibrillary Acidic Protein (GFAP) was discovered by Amico Bignami and co-workers as a major fibrous protein of multiple sclerosis plaques. It was subsequently found to be a member of the 10nm or intermediate filament (IF) family, specifically the IF family Class III, which also includes peripherin, desmin and vimentin. GFAP is strongly and specifically expressed in astrocytes and certain other astroglia in the CNS, in satellite cells, peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. In many damage and disease states GFAP expression is heavily upregulated in astrocytes. In addition, neural stem cells frequently strongly express GFAP. Point mutations in the protein coding region of the GFAP gene lead to Alexander disease which is characterized by the presence of abnormal astrocytes containing GFAP protein aggregates known as Rosenthal fibers. Therefore, GFAP antibody is ideal for investigators involved in neuropathologic diseases and more generally in Neuroscience.

免疫原: Anti-GFAP Antibody was produced in rabbit by repeated immunizations with recombinant and purified bovine glial fibrillary acidic protein.

保存建议: Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

其他: Rockland成立于1962年，是一家老牌抗体原产企业，其位于美国费城郊区的农场保有近20种实验动物。Rockland公司为生命科学领域提供丰富的、高质量的抗体，包括载脂蛋白、细胞周期/凋亡、细胞因子、细胞信号蛋白、酶类、细胞外基质、转录因子(NFkB)和泛素（Ubiquitin）等识别抗体，应用范围包括Western blot、免疫组化、免疫荧光和ELISA等。另外，Rockland也生产特别齐全的二抗，包括纯化、生物素、HRP/ALP、荧光标记二抗，应用十分广泛。