5-S)-HETE-d8 Lipid Maps MS Standard, 5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid
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Cayman
产品货号
10007276-500
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¥30912/500 ug
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背景资料
5-S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of 5-S)-HETE by GC- or LC-mass spectrometry -MS). 5-S)-HETE is produced by the action of 5-lipoxygenase on arachidonic acid to give 5-S)-HpETE, followed by reduction of the hydroperoxide. 5-S)-HETE has proliferative and chemotactic effects on granulocytes. When further metabolized to the 5-oxoETE, it is a more potent eosinophil chemoattractant than leukotriene B4.