DOPI-5-P1|Phosphatidylinositol-5-phosphate C-8, PtdIns--5)-P1 -1,2-dioctanoyl) -ammonium salt), 1-(1,2-dioctanoylphosphatidyl)inositol-5-phosphate, diammonium salt
供应商
Cayman
产品货号
10007758-5
产品报价
¥23520/5 mg
产品说明书
购买方式
产品新闻
背景资料
The phosphatidylinositol -PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns--5)-P1 -1,2-dioctanoyl) is a synthetic analog of natural PtdIns featuring C8:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol -DAG) stereochemistry as the natural compound. PtdIns--5)-P1 can be phosphorylated to di- -PtdIns-P2; PIP2) and triphosphates -PtdIns-P3; PIP3) by phosphoinositol -PI)-specific kinases. Hydrolysis of PtdIns--4,5)-P2 by PI-specific phospholipase C generates inositol triphosphate -IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade.
产品描述
A synthetic analog of natural PtdIns featuring C8:0 fatty acids at the sn-1 and sn-2 positions; contains the same inositol and DAG stereochemistry as the natural compound