中文名称

D-myo-Inositol-2,4,5-triphosphate -sodium salt) (5 mg)

英文名字

Ins(2,4,5)P3 (sodium salt)|2,4,5-IP3 (sodium salt), D-myo-Inositol-2,4,5-triphosphate -sodium salt), D-myo-inositol-2,4,5-tris(hydrogen phosphate), trisodium salt

供应商

Cayman

产品货号

10007779-5

产品报价

￥44590/5 mg

产品说明书

购买方式

产品新闻

背景资料

The inositol phosphates -InsP) play a critical role as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, D-myo-Inositol-2,4,5-triphosphate -sodium salt) -Ins-1,4,5)P3), more commonly referred to as IP3, is a second messenger produced in cells by phospholipase C -PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins-1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins-2,4,5)P3 is a metabolically stable analog of Ins-1,4,5)P3 that is commonly used to study Ca2+ signaling pathways. Ins-2,4,5)P3 acts as a partial agonist at rat hepatic IP3 receptors, exhibiting 65% of the maximal Ca2+ response obtained with Ins-1,4,5)P3.

产品描述

The inositol phosphates -InsP) play a critical role as small, soluble second messengers in the transmission of cellular signals.{8344,8672} The most studied InsP, Ins-1,4,5)P3, more commonly referred to as IP3, is a second messenger produced in cells by PLC-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate.{2429,5714} Binding of Ins-1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium.{5714,4096} Ins-2,4,5)P3 is a metabolically stable analog of Ins-1,4,5)P3 that is commonly used to study Ca2+ signaling pathways. Ins-2,4,5)P3 acts as a partial agonist at rat hepatic IP3 receptors, exhibiting 65% of the maximal Ca2+ response obtained with Ins-1,4,5)P3.{13732}

产品形式

保存建议

-20

其他

Cayman Chemical

注意

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