中文名称

D-myo-Inositol-1,2,6-triphosphate -sodium salt) (5 mg)

英文名字

Ins(1,2,6)-P3|1,2,6-IP3, D-myo-Inositol-1,2,6-triphosphate -sodium salt), D-myo-inositol-1,2,6-tris(hydrogen phosphate), trisodium salt

供应商

Cayman

产品货号

10007780-5

产品报价

￥24010/5 mg

产品说明书

购买方式

产品新闻

背景资料

D-myo-Inositol-1,2,6-phosphate -Ins-1,2,6)-P3) is a member of the inositol phosphate -InsP) family of second messengers that play a critical role in the transmission of cellular signals. The most studied InsP, Ins-1,4,5)-P3 is a second messenger produced in cells by phospholipase C -PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins-1,4,5)-P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins-1,2,6)-P3 -tested as the D/L racemic mixture) is ~1,000-fold less potent than Ins-1,4,5)-P3 at initiating Ca2+ release when injected into Xenopus oocytes.

产品描述

Ins-1,2,6)-P3 is a member of the inositol phosphate -InsP) family of second messengers that play a critical role in the transmission of cellular signals.{8344,8672} The most studied InsP, Ins-1,4,5)-P3 is a second messenger produced in cells by PLC-mediated hydrolysis of PtdIns-4,5-biphosphate.{2429,5714} Binding of Ins-1,4,5)-P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium.{5714,4096} Ins-1,2,6)-P3 -tested as the D/L racemic mixture) is ~1,000-fold less potent than Ins-1,4,5)-P3 at initiating Ca2+ release when injected into Xenopus oocytes.{13725}

产品形式

保存建议

-20

其他

Cayman Chemical

注意

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