DOPI|Phosphatidylinositol C-8, PtdIns--1,2-dioctanoyl) -sodium salt), 1-(1,2-dioctanoylphosphatidyl)inositol, monosodium salt
供应商
Cayman
产品货号
10008099-5
产品报价
¥23520/5 mg
产品说明书
购买方式
产品新闻
背景资料
The phosphatidylinositol -PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns--1,2-dioctanoyl) is a synthetic analog of natural PtdIns containing C8:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacyl glycerol -DAG) stereochemistry as that of the natural compound. The short fatty acid chains of this analog, compared to naturally-occurring PtdIns, gives it different physical properties including high solubility in aqueous media. PtdIns are phosphorylated to mono- -PtdIns-P; PIP), di- -PtdIns-P2; PIP2), and triphosphates -PtdIns-P3; PIP3). Hydrolysis of PtdIns--4,5)-P2 by phosphoinositide -PI)-specific phospholipase C generates inositol triphosphate -IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade.
产品描述
A synthetic analog of natural PtdIns containing C8:0 fatty acids at the sn-1 and sn-2 positions; contains the same inositol and DAG stereochemistry as the natural compound