Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP10 (stromelysin 2) degrades a broad range of substrates including gelatin, collagen types III, IV and V, fibronectin, aggrecan, and pig cartilage proteoglycan. MMP10 can activate other MMPs such as MMP1 and MMP8. MMP10 is expressed in keratinocytes, T cells, menstrual endometrium and a few tumor samples. Structurally, MMP10 may be divided into four distinct domains: a prodomain which is cleaved upon activation, a catalytic domain containing the zinc binding site; a short linker region, and a carboxyl terminal hemopexin- slike domain.
应用类型
WB, IHC (P)
免疫原
该Anti-Human MMP-10的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human MMP-10的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human MMP-10的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human MMP-10的详细信息查看ReliaTech提供的产品说明书。溶解建议:Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.