Anti-Human FGF-19-Anti-Human FGF-19代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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一抗

开云·官方站线上登录平台入口_开云(中国)

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背景资料: Human FGF19 cDNA predicts a 251 aa precursor protein with a 22 aa signal peptide and a 229 aa secreted mature protein with no potential N-linked glycosylation sites. Among FGF family members, human FGF19 is most closely related to chicken FGF19 and murine FGF15, sharing approximately 61% and 51% aa sequence identity, respectively. Neither the human orthologue of mouse FGF15, nor the mouse counterpart of human FGF19 has been identified. With the exception of adult gall bladder epithelium, FGF19 expression is restricted to fetal tissues. Unlike most FGFs which bind to and activate more than one FGF receptor, FGF19 is a specific ligand for FGF R4. Similarly, another FGF family member, FGF7 (KGF), only activates KGF R, the IIIb isoform of FGF R2. During chick embryogenesis, FGF19 has been shown to act synergistically with Wnt8c to initiate inner ear development.

保存建议: 该Anti-Human FGF-19的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

其他: ReliaTech全称为受体配体技术有限公司 (Receptor Ligand Technologies GmbH)，1999年成立，总部位于德国不伦瑞克，是一家后基因组生物技术公司。ReliaTech主要专注于受体和配体的发现与研究。此外，ReliaTech也开发应用于血管与淋巴管生成研究的相关高品质试剂。目前ReliaTech提供近2800款产品，产品线主要包括重组蛋白(细胞因子、生长因子、可溶性受体)、抗体、ELISA试剂盒等。