GFR alpha -1, -2, -3, and -4 are GPI-anchored receptors that interact preferentially with the GDNF family ligands GDNF, Neurturin, Artemin, and Persephin, respectively. GFR alpha proteins initiate signaling in association with the receptor tyrosine kinase RET and by RET-independent pathways. GFR alpha-mediated signaling is instrumental in the differentiation, migration, and support of central and peripheral neurons. Alternative splicing generates multiple isoforms of GFR alpha proteins.
应用类型
ELISA, IHC (F)
免疫原
该Anti-Mouse GFR 4 alpha的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Mouse GFR 4 alpha的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Mouse GFR 4 alpha的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Mouse GFR 4 alpha的详细信息查看ReliaTech提供的产品说明书。溶解建议:Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.