Talin is a high-molecular-weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts. Talin serves a function of linking vinculin to the integrins, and, thus, the cytoskeleton to extracellular matrix (ECM) receptors. It has a mass of 270 kD and shares 23% N-terminal identity with ezrin, which has similar functions. TLN gene is mapped to 9p. This antibody is suitable for researchers interested in cell signaling, membrane biology, and growth factor research.
应用类型
ELISA,Western Blot,
免疫原
Talin antibody was produced in mice by repeated immunizations with purified chicken gizzard talin.
来源宿主
Mouse
反应性
Bovine (Bos Taurus); H. sapiens (Human)
保存建议
Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.