ZIPK抗体-ZIPK Antibody （DAPK3， FLJ36473， ZIP， ZIPK， death-associated protein kinase 3）代理/参数/厂家-二抗-开云·官方站线上登录平台入口

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二抗

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英文名字: ZIPK Antibody （DAPK3， FLJ36473， ZIP， ZIPK， death-associated protein kinase 3）

背景资料: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases，such as ASK-1 and RIP，are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase. ZIP kinase contains an N-terminal kinase domain and a C-terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREB family. ZIP kinase has high sequence homology to DAP kinase （death-associated protein kinase），which is a mediator of apoptosis induced by gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family，which mediates apoptosis through their catalytic activities. The messenger RNA was ubiquitously expressed in various tissues.

应用类型: Immunocytochemistry: 10 ug/ml； Western Blot: 0.5 – 1 ug/ml； ELISA. However， the optimal conditions should be determined individually.

免疫原: Peptide corresponding to amino acids near the center of human ZIP Kinase.

保存建议: 提供的ZIPK抗体产品为无色溶液形式，含有100 ug抗体.该产品浓度为1 mg/ml，溶解于包含有0.02 % 叠氮化钠的PBS缓冲液中.请在收到该ZIPK抗体产品后，将其置于-20 °C冷冻保存，建议分装使用以避免反复冻融.

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