DRAM抗体（N末端）-DRAM Antibody （NT）（Damage-regulated autophagy modulator）代理/参数/厂家-二抗-开云·官方站线上登录平台入口

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二抗

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背景资料: Damage-regulated autophagy modulator （DRAM） is a p53 target gene encoding a lysosomal protein that induces autophagy，a process that degrades cytosolic proteins and organelles. It has been suggested that activation of DRAM by p53 is simultaneous to the activation by p53 of one or more proapoptotic genes such as PUMA，Bax，etc.，and that the signaling pathways regulated by these genes promote a full cell death response. By itself，DRAM cannot induce apoptosis，but the fact that it is inactivated in certain cancers highlights the importance of DRAM and suggests that autophagy may play a more important role in cancer than initially suspected. At least two different isoforms of DRAM are known to exist.

应用类型: Western Blot: 0.5-2 ug/ml， Immunohistochemistry: 2.5 ug/ml， ELISA. However， the optimal conditions should be determined individually.

免疫原: DRAM antibody was raised against a 16 amino acid peptide from near the amino terminus of human DRAM.

保存建议: 提供的DRAM抗体（N末端）产品为无色溶液形式，含有100 ug抗体.该产品浓度为1 mg/ml，溶解于包含有0.02 % 叠氮化钠的PBS缓冲液中.请在收到该DRAM抗体（N末端）产品后，将其置于-20 °C冷冻保存，建议分装使用以避免反复冻融.

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