GZF1 Antibody (CT) (GDNF-inducible zinc finger protein 1, ZNF336, ZBTB23)
供应商
Biovision
产品货号
5298-100
产品报价
¥已停产
产品说明书
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产品新闻
背景资料
The GDNF-inducible zinc finger protein 1 (GZF1) is a sequence-specific transcriptional repressor with a BTB/POZ domain and ten zinc finger motifs whose expression is required for renal branching morphogenesis during kidney development. GZF1 binds to the 5¡¯ regulatory region of the homeodomain protein HOXA10,suggesting that GZF1 may play a role in morphogenesis other than kidney development. Recent experiments have indicated that GZF1 associates with nucleolin and this association is mediated by the first four zinc finger motifs of GZF1. It is thought that Nucleolin modulates the subcellular localization of GZF1 as well as its transcriptional repressor activity.
应用类型
Western Blot: 1 - 2 ug/ml, ELISA. However, the optimal conditions should be determined individually.
免疫原
GZF1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human GZF1.