SGSM1 Antibody (Center) (Small G protein signaling modulator 1, RUTBC2)
供应商
Biovision
产品货号
5314-100
产品报价
¥已停产
产品说明书
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产品新闻
背景资料
Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM1 (RUTBC2) is a 1,148 amino acid protein that localizes to the Golgi apparatus and is mainly expressed in the CNS. SGSM1 interacts with RAP and RAB subfamily members of the small G proteins,and function as modulators of RAP and RAB-mediated neuronal signal transduction and vesicular transportation pathways.
应用类型
Western Blot: 1 - 2 ug/ml, ELISA. However, the optimal conditions should be determined individually.
免疫原
SGSM1 antibody was raised against a 17 amino acid synthetic peptide near the center of human SGSM1.