【干冰】Anti-Eaat2 (GOAT) Antibody - 600-101-MN3S-【干冰】Anti-Eaat2 (GOAT) Antibody - 600-101-MN3S代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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一抗

开云·官方站线上登录平台入口_开云(中国)

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背景资料: SLC1A2 (Solute Carrier Family 1 Member 2), glutamate transporters, also known as excitatory amino acid transporters (EAATs), are sodium- and potassium- dependent members of the solute carrier family 6 (SLC1), widely distributed throughout the brain. These sodium-dependent, high-affinity amino acid transporter mediates the uptake of L-glutamate, L-aspartate, and D-aspartate functioning as a symporter that transports one amino acid molecule together with two or three Na (+) ions and one proton, in parallel with the counter-transport of one K (+) ion. It mediates the Cl (-) flux that is not coupled to amino acid transport avoiding the accumulation of negative charges due to aspartate and Na (+) symport. Eaat2 is essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate. Improper regulation of this gene is thought to be associated with several neurological disorders including Epileptic Encephalopathy, Early Infantile, 41 and Undetermined Early-Onset Epileptic Encephalopathy. Anti-Eaat2 Antibody is useful for researchers interested in transmembrane transporter activity, neuroscience research, and cell metabolism.

免疫原: Anti-Eaat2 Antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to the N-terminal region of Rat Eaat2 surrounding aa1-25 conjugated to Keyhole Limpet Hemocyanin (KLH).

保存建议: Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 µL). To minimize loss of volume dilute 1:10 by adding 225 µL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.

其他: Rockland成立于1962年，是一家老牌抗体原产企业，其位于美国费城郊区的农场保有近20种实验动物。Rockland公司为生命科学领域提供丰富的、高质量的抗体，包括载脂蛋白、细胞周期/凋亡、细胞因子、细胞信号蛋白、酶类、细胞外基质、转录因子(NFkB)和泛素（Ubiquitin）等识别抗体，应用范围包括Western blot、免疫组化、免疫荧光和ELISA等。另外，Rockland也生产特别齐全的二抗，包括纯化、生物素、HRP/ALP、荧光标记二抗，应用十分广泛。