Androgen Receptor Antibody (Clone 549CT16.1.4) (AR; DHTR; NR3C4; Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4)
供应商
Biovision
产品货号
6711-100
产品报价
¥已停产
产品说明书
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产品新闻
背景资料
Androgens exhibit a wide range of effects on the development,maintenance and regulation of male phenotype and reproductive physiology in males. The androgen receptor (AR) is a member of the steroid superfamily of ligand-dependent transcription factors. ARs bind active testosterone (T) and dihydrotestosterone (DHT). The rates of association and dissociation of T are about 3 times more rapid than those of DHT. This difference in binding kinetics may account for the different physiological effects of T and DHT. Androgen binding results in an at least 6-fold increase in androgen receptor stability.
应用类型
Western blot: ~1:100 – 1:250
免疫原
Purified His-tagged Androgen Receptor Protein (Fragment) was used to produce this monoclonal antibody.