AKR1A1 Antibody (CT) (AKR1A1; ALDR1; ALR; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Aldo-keto reductase family 1 member A1)
供应商
Biovision
产品货号
6738-100
产品报价
¥已停产
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产品新闻
背景资料
AKR1A1 (aldo-keto reductase family 1 member A1),also known as ALR (aldehyde reductase),DD3 (dihydrodiol dehydrogenase 3) or ALDR1 (alcohol dehydrogenase),is a widely and abundantly expressed member of the aldo-keto reductase (AKR) family of proteins. Members of the AKR family are soluble NADPH-dependent oxidoreductases. They play important roles in the metabolism of drugs,carcinogens and reactive aldehydes. AKR1A1 exists as a monomer and catalyzes the reduction of xenobiotic and biogenic aldehydes and ketones to their corresponding alcohols. In particular,AKR1A1 efficiently catalyzes medium-chain and aromatic aldehydes. AKR1A1 participates in the biosynthetic pathways of cholesterol and triglyceride and plays a role in the activation of polycyclic aromatic hydrocarbons (PAHs).
应用类型
Western blot: ~1:1000, IHC: ~1:10 – 1:50
免疫原
This AKR1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-325 amino acids from the C-terminal region of human AKR1A1.