AKR1B1抗体（C末端）-AKR1B1 Antibody （CT）（AKR1B1； ALDR1； Aldose reductase； Aldehyde reductase； Aldo-keto reductase family 1 member B1.）代理/参数/厂家-二抗-开云·官方站线上登录平台入口

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二抗

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英文名字: AKR1B1 Antibody （CT）（AKR1B1； ALDR1； Aldose reductase； Aldehyde reductase； Aldo-keto reductase family 1 member B1.）

背景资料: Aldose reductase （also designated AKR1B1，ALDR1，ALR2 or AR） is member of the monomeric NADPH-dependent aldoketoreductase family. Aldose reductase，which has a molecular mass of 36 kDa，catalyzes the reduction of various aldehydes and has been implicated in the development of diabetic complications by catalyzing the reduction of the aldehyde form of glucose，to the corresponding sugar alcohol，sorbitol. This pathway plays a minor role in glucose metabolism in most tissues，however in diabetic hyperglycemia，cells undergoing insulin-independent uptake of glucose accumulate significant quantities of sorbitol. The resulting hyperosmotic stress to cells may be a cause of diabetic complications such as neuropathy，retinopathy，and cataracts. Aldose reductase is very similar to human aldehyde reductase，bovine prostaglandin F synthase and to the European common frog protein，rho-crystallin.

免疫原: This AKR1B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-316 amino acids from the C-terminal region of human AKR1B1.

保存建议: 提供的AKR1B1抗体（C末端）产品为无色溶液形式，含有100 ul抗体.该产品浓度为与批次相关，溶解于包含有0.09% （W/V）叠氮化钠的PBS缓冲液中.请在收到该AKR1B1抗体（C末端）产品后，将其置于-20 °C冷冻保存，建议分装使用以避免反复冻融.

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