烟碱型乙酰胆碱受体Beta1（胞外）抗体（25 ul）-Anti-Nicotinic Acetylcholine Receptor Beta1 （extracellular)代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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背景资料: nAChRs are formed by the assembly of five transmembrane subunits, selected from a pool of 17 homologous polypeptides (α1-10, β1-4, γ, δ, and ε). There are many nAChR subtypes, each consisting of a specific combination of subunits, which mediate diverse physiological functions. They are widely expressed in the central nervous system, while, in the periphery, they mediate synaptic transmission at the neuromuscular junction and ganglia. nAChRs are also found in non-neuronal/non-muscle cells (keratinocytes, epithelia, macrophages, etc. ). Structurally, all subunits have the following: a conserved large extracellular N-terminal domain, conserved transmembrane domains, a variable cytoplasmic loop and a fourth transmembrane domain with a short extracellular C-terminal domain. An active nAChR is generally a heteropentamer of these various subunits organized around a central pore

免疫原: Nicotinic Acetylcholine 受体 Beta1 (胞外)抗体的免疫原肽段为(C)EKDEEMSTKVYLD。此免疫原序列来源于68-80 位氨基酸残基，该序列来源于大鼠nAChRβ1 (Accession编号为P25109)。胞外，N端。

保存建议: 艾美捷为您提供的Nicotinic Acetylcholine 受体 Beta1 (胞外)抗体(25 ul)为室温运输，建议您收到产品后﹣20℃保存。

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