Brain-Derived Neurotrophic Factor (BDNF) is a member of the NGF family of neurotrophic growth factors, and shares high sequence homology with NGF, NT-3 and NT-4/5. BDNF is found in neurons of the central nervous system. It is expressed predominantly in hippocampus, cortex, and amygdaloid complex. nThe synthesis of BDNF is subject to regulation by neuronal activity and specific transmitter systems. nBDNF binds to p75NTR, the neurotrophin receptor, and may initiate programmed cell death by acting through this receptor. Signal transduction is activated by the dimerization and autophosphorylation of the TrkB receptor.
产品描述
Human Brain-Derived Neurotrophic Factor, Recombinant, E. coli
产品形式
Brain-Derived Neurotrophic Factor (BDNF) is a member of the NGF family of neurotrophic growth factors, and shares high sequence homology with NGF, NT-3 and NT-4/5. BDNF is found in neurons of the central nervous system. It is expressed predominantly in hippocampus, cortex, and amygdaloid complex. nThe synthesis of BDNF is subject to regulation by neuronal activity and specific transmitter systems. nBDNF binds to p75NTR, the neurotrophin receptor, and may initiate programmed cell death by acting through this receptor. Signal transduction is activated by the dimerization and autophosphorylation of the TrkB receptor.
保存建议
艾美捷为您提供的Alonmone Labs原装进口的human BDNF (5 x 1 µg)产品可室温运输,建议您在收到产品后将其置于合适的温度下保存。