中文名称

布雷菲德菌素A（5 x 1毫克）

英文名字

Brefeldin A

供应商

Alomone

产品货号

ALO-B-275-5x1

产品报价

￥已停产

产品说明书

购买方式

银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868

产品新闻

背景资料

Brefeldin A (BFA), is a macrocyclic lactone synthesized from palmitate (C16) by a variety of fungi. It was initially isolated and characterized in the 1960's as an antiviral antibiotic. In the late 1980's, it was found to act as a very powerful inhibitor of intracellular protein transport.BFA specifically and reversibly blocks protein transport from the endoplasmic reticulum (ER) to the Golgi apparatus in many cell types and species. These effects are generally accompanied by distinct structural changes expressed in apparent collapse of the Golgi stacks and its redistribution into the ER as well as into nuclear envelope, which leads to inhibition of protein secretion, vesicular assembly and antigen presentation. A large body of evidence demonstrates that BFA inhibits the whole cell membrane traffic by its ability to inhibit binding of regulatory coat proteins to their target organelles. In this way, BFA deregulates membrane traffic throughout the central vacuolar system of the cell.

产品描述

Protein Synthesis and Transport Inhibitor

产品形式

Brefeldin A (BFA), is a macrocyclic lactone synthesized from palmitate (C16) by a variety of fungi. It was initially isolated and characterized in the 1960's as an antiviral antibiotic. In the late 1980's, it was found to act as a very powerful inhibitor of intracellular protein transport.BFA specifically and reversibly blocks protein transport from the endoplasmic reticulum (ER) to the Golgi apparatus in many cell types and species. These effects are generally accompanied by distinct structural changes expressed in apparent collapse of the Golgi stacks and its redistribution into the ER as well as into nuclear envelope, which leads to inhibition of protein secretion, vesicular assembly and antigen presentation. A large body of evidence demonstrates that BFA inhibits the whole cell membrane traffic by its ability to inhibit binding of regulatory coat proteins to their target organelles. In this way, BFA deregulates membrane traffic throughout the central vacuolar system of the cell.

保存建议

艾美捷为您提供的Alonmone Labs原装进口的Brefeldin A (5 x 1 mg)产品可室温运输，建议您在收到产品后将其置于合适的温度下保存。

其他

Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证，以冻干粉形式提供，可确保产品生物活性和保质期。Alomone可提供多种包装规格，灵活方便。作为Alomone Labs在中国的区域总代理，开云·官方站线上登录平台入口_开云(中国) 将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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