中文名称

欧米茄芋螺毒素MVIIC（1毫克）

英文名字

Omega-Conotoxin MVIIC

供应商

Alomone

产品货号

ALO-C-150-1

产品报价

￥已停产

产品说明书

购买方式

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产品新闻

背景资料

ω-Conotoxin MVIIC, blocks CaV2.1 (α1A, P/Q-type) and Cav2.2 (α1B, N-type) channels. The toxin binds with high affinity to Cav2.1 and with lower affinity to Cav2.2 in rabbit brain. However, the block by ω-Conotoxin-MVIIC, of N-type channels in DRG neurons developed much faster than the block of P-type currents in Purkinje cells. The effect of the toxin is modulated by voltage (i.e. it is more potent for inactivated channels). In addition this toxin was reported to block nicotinic receptors (transiently expressed in Xenopus oocytes) with IC50 of 1.3 µM. It was also shown to inhibit K+-induced 3H-GABA release in hippocampus in vivo. This effect was with high affinity (50% block, 200 nM). The toxin was used to inhibit synaptic transmission in several peripheral preparations.

产品描述

A Blocker of Presynaptic CaV (N-type and P/Q type) Channels

产品形式

ω-Conotoxin MVIIC, blocks CaV2.1 (α1A, P/Q-type) and Cav2.2 (α1B, N-type) channels. The toxin binds with high affinity to Cav2.1 and with lower affinity to Cav2.2 in rabbit brain. However, the block by ω-Conotoxin-MVIIC, of N-type channels in DRG neurons developed much faster than the block of P-type currents in Purkinje cells. The effect of the toxin is modulated by voltage (i.e. it is more potent for inactivated channels). In addition this toxin was reported to block nicotinic receptors (transiently expressed in Xenopus oocytes) with IC50 of 1.3 µM. It was also shown to inhibit K+-induced 3H-GABA release in hippocampus in vivo. This effect was with high affinity (50% block, 200 nM). The toxin was used to inhibit synaptic transmission in several peripheral preparations.

保存建议

艾美捷为您提供的Alonmone Labs原装进口的Omega-Conotoxin MVIIC (1 mg)产品可室温运输，建议您在收到产品后将其置于合适的温度下保存。

其他

Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证，以冻干粉形式提供，可确保产品生物活性和保质期。Alomone可提供多种包装规格，灵活方便。作为Alomone Labs在中国的区域总代理，开云·官方站线上登录平台入口_开云(中国) 将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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