Roscovitine is an olomoucine-related purine flavopiridol, and is a highly potent inhibitor for the kinase activity of CDK1, CDK2, CDK5, and CDK7 (IC50 ~ 0.5- 0.2 µM) but is a poor inhibitor for CDK 4 and CDK 6 (IC50 > 100 µM).
产品描述
A Cyclin Dependent Kinase (CDK) Inhibitor, and a T-Type CaV Blocker
产品形式
Roscovitine is an olomoucine-related purine flavopiridol, and is a highly potent inhibitor for the kinase activity of CDK1, CDK2, CDK5, and CDK7 (IC50 ~ 0.5- 0.2 µM) but is a poor inhibitor for CDK 4 and CDK 6 (IC50 > 100 µM).