Mouse Anti Human C-type lectin domain family 4 member E
供应商
Prospec
产品货号
ANT-012
产品报价
¥询价/100ug ¥20ug ¥5ug
产品说明书
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产品新闻
背景资料
CLEC4E (MINCLE or CLECSF9), belongs to a diverse family of proteins which were originally defined by their ability to recognize a wide range of ligands of carbohydrate structure. MINCLE is expressed in macrophages subjected to several types of stress. CLEC4E has an important role in response to trehalose-6,6’’-dimycolate (TDM) and activated by a synthetic analogue, trehalose dibehenate (TDB). It was reported recently that MINCLE is connected with an immunoreceptor tyrosine-based activation motif–containing Fc receptor Y chain (FcRY) and functions as an activating receptor for damaged self- and non–self-pathogenic fungi.
应用类型
ELISA, Western blot and Immunofluorescence
免疫原
Anti-human CLEC4E mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CLEC4E amino acids 41-219 purified from E. coli.