Mouse Anti Human Pyridoxamine 5’-Phosphate Oxidase
供应商
Prospec
产品货号
ANT-063
产品报价
¥询价/100ug ¥20ug ¥5ug
产品说明书
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产品新闻
背景资料
Pyridoxine-5’-phosphate oxidase (PNPO) is the rate-limiting enzyme in vitamin B6 synthesis. Vitamin B6 (Pyridoxal 5-prime-phosphate or PLP) is vital for normal cellular function, and some cancer cells have notable differences in vitamin B6 metabolism compared to their normal counterparts.Vitamin B6 is an essential co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in the PNPO gene result in PNPO deficiency, a form of neonatal epileptic encephalopathy.
应用类型
ELISA, Western blot
免疫原
Anti-human PNPO mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PNPO amino acids 57-261 purified from E. coli.