非那明产品是Fexaramine is a potent, selective farnesoid X receptor (FXR) agonist (EC₅₀ = 25 nM). It displays no activity at hRXRα, hPPARα, hPPARγ, hPPARδ, mPXR, hPXR, hLXRα, hTRβ, hRARβ, mCAR, mERRγ and hVDR receptors. Fexaramine also demonstrates 100-fold increased affinity to FXR compared to endogenous bile acids .