Recombinant Human GTPase Activating Protein (SH3 domain) Binding Protein 1
供应商
ProSpec
产品货号
ENZ-048
产品报价
¥询价/10ug ¥1mg ¥2ug
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产品新闻
背景资料
G3BP1 belongs to the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. G3BP1 is one of the DNA-unwinding enzymes that favors partially unwound 3’-tailed substrates and is also able to unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. G3BP1 binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. In addition, G3BP1 cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3’-UTR.