Recombinant Human 3(2) 5-Bisphosphate Nucleotidase 1
供应商
ProSpec
产品货号
ENZ-061
产品报价
¥询价/10ug ¥1mg ¥2ug
产品说明书
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产品新闻
背景资料
BPNT1 belongs to the magnesium-dependent, lithium-sensitive phosphomono-esterase superfamily. BPNT1 catalyzes the conversion of PAPS(adenosine 3’-phosphate 5’ phosphosulfate) to APS(adenosine 5’-phosphosulfate) and the conversion of PAP(3’(2’)-phosphoadenosine 5’ phosphate) to AMP(adenosine 5’-phosphate) using magnesium as a cofactor. BPNT1 is expressed everywhere but at maximum levels in brain and kidney. BPNT1 is potently inhibited by lithium, a drug used for the treatment of manic depression and bipolar affective disorder, which suggests that BPNT1 has a possible role in the etiology of mood disorders.