Recombinant Human Ubiquitin-Conjugating Enzyme E2I
供应商
ProSpec
产品货号
ENZ-341
产品报价
¥询价/10ug ¥1mg ¥50ug
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产品新闻
背景资料
Human Ubc9 is homologous to ubiquitin-conjugating enzymes(E2s). However, instead of conjugating ubiquitin, it conjugates a ubiquitin homologue, small ubiquitin-like modifier 1(SUMO-1). And hUbc9 retains striking structural and functional conservation with yeast Ubc9. The ubiquitin-dependent protein degradation system has been recognized as a complete enzymatic pathway that is responsible for the selective degradation of abnormal and short-lived proteins. The conjugation of ubiquitin requires the activities of ubiquitin-activating(E1) and –conjugating(E2) enzymes.