Recombinant Human Aldo-Keto Reductase Family 1 Member A1
供应商
ProSpec
产品货号
ENZ-464
产品报价
¥询价/1mg ¥20ug ¥5ug
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产品新闻
背景资料
AKR1A1 is part of the aldo/keto reductase superfamily, it catalyzes the NADPH-dependent reduction from a range of aromatic and aliphatic aldehydes to their related alcohols. AKR1A1 corresponds(65% identity) to aldose reductase, an enzyme that takes part in the pathogenesis of some diabetic and galactosemic complications. AKR1A1 is involved in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin and daunorubicin.