Recombinant Human Ubiquitin-Conjugating Enzyme E2F
供应商
ProSpec
产品货号
ENZ-625
产品报价
¥询价/1mg ¥20ug ¥5ug
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产品新闻
背景资料
Ubiquitin-conjugating enzyme E2 F(UBE2F) is a member of the ubiquitin-conjugating enzyme family and UBE2F subfamily. Ubiquitin-conjugating enzymes or sometimes as ubiquitin-carrier enzymes, run the second step in the ubiquitination reaction which targets a protein for degradation using the proteasome. The UBE2F receives the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins.
RBX2-UBE2F complex neddylates specific target proteins, for example CUL5 as can be seen from the specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1.