Recombinant Human Protein Phosphatase 1, Regulatory Subunit 8
供应商
ProSpec
产品货号
ENZ-648
产品报价
¥询价/10ug ¥1mg ¥2ug
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产品新闻
背景资料
Protein Phosphatase 1, Regulatory Subunit 8(PPP1R8) is the RNA-binding subunit of a key species of protein phosphatase-1 in the nucleus. The PPP1R8 enzyme is an inhibitor subunit of the main nuclear protein phosphatase-1(PP-1). PPP1R8 has RNA-binding activity however it doesn’t cleave RNA and may target PP-1 to RNA-associated substrates. Two isoforms of the PPP1R8 protein are specific inhibitors of type 1 serine/threonine protein phosphatases which can bind but not cleave RNA. The third isoform of the PPP1R8 protein is deficient in of the phosphatase inhibitory activity nonetheless it is a single-strand endoribonuclease comparable to RNase E of E. coli.