Recombinant Human Mercaptopyruvate Sulfurtransferase
供应商
ProSpec
产品货号
ENZ-676
产品报价
¥询价/1mg ¥20ug ¥5ug
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背景资料
Mercaptopyruvate Sulfurtransferase(MPST) catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. MPST might be involved in cysteine degradation and cyanide detoxification. The MPST enzyme is regulated by oxidative stress and thioredoxin. In oxidative stress conditions, the catalytic cysteine site is transformed to a sulfenate which inhibits the MPST enzyme activity. The reduced thioredoxin cleaves an intersubunit disulfide bond to activate the redox switch and reactivate the enzyme. A deficiency in MPST activity is implicated in a rare inheritable condition known as MCDU(mercaptolactate-cysteine disulfiduria).