Recombinant E.Coli G/U Mismatch-Specific DNA Glycosylase
供应商
ProSpec
产品货号
ENZ-703
产品报价
¥询价/10ug ¥1mg ¥2ug
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产品新闻
背景资料
G/U mismatch-specific DNA glycosylase(mug) is a part of the TDG/mug DNA glycosylase family. Mug is necessary for DNA damage lesion repair in stationary-phase cells. Mug protein removes three N4-ethenocytosine and takes away s the uracil base from mismatches in the order of U:G>U:A. The enzyme Uracil-N-Glycosylase removes uracil from the DNA leaving an AP position. Mug is also able to hydrolyzing the carbon-nitrogen bond among the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine plays a role in substrate recognition.