3’ to 5’ Exonuclease Activity Assay (Fluorometric)
供应商
Biovision
产品货号
K175-100
产品报价
¥询价/100assays
产品说明书
购买方式
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产品新闻
背景资料
待更新
产品描述
Exonucleases remove a single nucleotide or an oligonucleotide at the 5’ or 3’ end. Exonuclease, such as Three Prime Repair Exonuclease 1 (TREX1), plays an important role in proofreading of DNA amplification and removal of damaged DNA. Deficiency of TREX1 enzyme has been shown to trigger autoimmune disease, Aicardia-Goutieres syndrome. TREX1 expression has been reported to correlate with cervical cancer cell growth and disease progression. In addition, 3’ exonucleases are often used as tools in molecular biology such as site-directed mutagenesis and the generation of single stranded DNA probe. BioVision’s 3’ to 5’ Exonuclease Activity Assay Kit provides a quick and easy method for monitoring 3’ exonuclease activities in a wide variety of samples. In this assay, exonuclease digests the provided DNA probe, producing a strong fluorescent signal (Ex/Em= 304/369nm). The kit is simple, sensitive, high-throughput adaptable and can detect as low as 0.2 µU of exonuclease activity.
产品特点
Sensitive, High-throughput adaptable, Detection limit as low as 0.2