The EpiQuik超级甲基化DNA免疫共沉淀试剂盒是一个完整的、优化的试剂组合,它可以用过便捷地微孔板富集和捕获甲基化的DNA片段,此产品是 Methylamp MeDIP Kit试剂盒的改进产品,在敏感度和特异性方面有了很大改进,同时背景也减弱了.此试剂盒采用5-甲基氨基酸特异性抗体来沉淀甲基化的DNA.被富集的甲基化片段可以用来进行基因组范围内的特定基因的甲基化分析.此试剂盒富集的DNA可以被用于很多下游的实验,如甲基化DNA免疫共沉淀PCR、甲基化DNA免疫共沉淀芯片和甲基化DNA测序
已发表的部分文献: 标题:Dynamic integrated analysis of DNA methylation and gene expression profiles in in vivo and in vitro fertilized mouse post-implantation extraembryonic and placental tissues.作者:Tan K, Zhang Z, Miao K, Yu Y, Sui L, Tian J, An L;杂志名称:Mol Hum Reprod 标题:Dynamic comparisons of high-resolution expression profiles highlighting mitochondria-related genes between in vivo and in vitro fertilized early mouse embryos.作者:Ren L, Wang Z, An L, Zhang Z, Tan K, Miao K, Tao L, Cheng L, Zhang Z, Yang M, Wu Z, Tian J;杂志名称:Hum Reprod 标题:Methylation Status of Interleukin-6 Gene Promoter in Patients with Behçet's Disease.作者:Alipour S, Sakhinia E, Khabbazi A, Samadi N, Babaloo Z, Azad M, Abolhasani S, Farhadi J, Jadideslam G, Roshanravan N, Nouri M;杂志名称:Reumatol Clin 标题:The expression and methylation status of vitamin D receptor gene in Behcet's disease.作者:Shirvani SS, Nouri M, Sakhinia E, Babaloo Z, Jadideslam G, Shahriar A, Farhadi J, Khabbazi A;杂志名称:Immun Inflamm Dis 标题:Analysis of Methylation and Expression Profile of FOXP3 Gene in Patients with Behçet’s Syndrome作者:Farhadi J. et al;杂志名称:Iran J Allergy Asthma Immuno 标题:Investigation of promoter methylation of MCPH1 gene in circulating cell-free DNA of brain tumor patients.作者:Ghodsi M, Shahmohammadi M, Modarressi MH, Karami F;杂志名称:Exp Brain Res 标题:DNA methylation and hydroxymethylation associated with gene expression regulatory network during 3-methylcholanthrene induced lung cell malignant transformation.作者:Chen HQ, Chen DJ, Li Y, Han F, Jiang X, Cao J, Liu JY, Liu WB;杂志名称:Sci Total Environ 标题:DNMT1-mediated NR3C1 DNA methylation enables transcription activation of connexin40 and augments angiogenesis during colorectal cancer progression.作者:Zhai P, Zhang H, Li Q, Yang M, Guo Y, Xing C;杂志名称:Gene Epigentek 公司是全球领先的表观遗传学相关研究的技术创新者和产品开发供应商。开发了超过700多个专利产品,为表观遗传学方面的研究和新药研发提供全面系统的解决方案,涵盖样品制备、DNA/RNA甲基化(5-mc, 5-hmc, 5-fc, m6A)/DNMT分析、ChIP、组蛋白甲基化/乙酰化/去乙酰化/磷酸化/SUMO-等领域,提供小分子抑制剂、蛋白质、抗体、以及分析试剂盒产品。