Human CellExp™ VEGF R2 / KDR, Fc Tag Mouse Recombinant
供应商
Biovision
产品货号
P1259-20
产品报价
¥已停产
产品说明书
购买方式
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产品新闻
背景资料
Kinase insert domain receptor (KDR) is also known as CD309, FLK1, VEGFR, VEGFR2, and is one of the subtypes of VEGFR. VEGF receptors are receptors for vascular endothelial growth factor (VEGF). The VEGF receptors have an extracellular portion consisting of 7 immunoglobulin-like domains, a single transmembrane spanning region and an intracellular portion containing a split tyrosine-kinase domain. VEGF-A binds to VEGFR-1 (Flt-1) and VEGFR-2 (KDR/Flk-1). VEGFR-2 appears to mediate almost all of the known cellular responses to VEGF.The function of VEGFR-1 is less well defined, although it is thought to modulate VEGFR-2 signaling. Another function of VEGFR-1 may be to act as a dummy/decoy receptor, sequestering VEGF from VEGFR-2 binding (this appears to be particularly important during vasculogenesis in the embryo). In addition, VEGFR2 is able to interact with HIV-1 extracellular Tat protein upon VEGF activation, and seems to enhance angiogenesis in Kaposi's sarcoma lesions.
序列
提供的人CellExp™VEGF R2 / KDR,Fc标签小鼠重组Human CellExp™ VEGF R2 / KDR, Fc Tag Mouse Recombinant 是Biovision品牌中国区域总代理艾美捷科技产品,具体的蛋白序列可查看提供的英文版本产品说明书。
来源宿主
提供的人CellExp™VEGF R2 / KDR,Fc标签小鼠重组Human CellExp™ VEGF R2 / KDR, Fc Tag Mouse Recombinant 产品来源宿主,查看该产品说明书,或者在线咨询我们。
溶解建议
Centrifuge the vial prior to opening. Reconstitute in sterile deionized water.