Human CellExp™Flt-3 / Flk-2, Fc Tag, Human Recombinant
供应商
Biovision
产品货号
P1459-50
产品报价
¥已停产
产品说明书
购买方式
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产品新闻
背景资料
Flt-3(Receptor-type tyrosine-protein kinase FLT3) is also known as FLK-2(Fetal liver kinase-2), STK-1(Stem cell tyrosine kinase 1), CD135. FLT3 is a cytokine receptor which belongs to the receptor tyrosine kinase class III. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.
序列
提供的Human CellExp™Flt-3 / Flk-2,Fc标签,人类重组Human CellExp™Flt-3 / Flk-2, Fc Tag, Human Recombinant是Biovision品牌中国区域总代理艾美捷科技产品,具体的蛋白序列可查看提供的英文版本产品说明书。
来源宿主
提供的Human CellExp™Flt-3 / Flk-2,Fc标签,人类重组Human CellExp™Flt-3 / Flk-2, Fc Tag, Human Recombinant产品来源宿主,查看该产品说明书,或者在线咨询我们。
溶解建议
Reconstitute in sterile deionized water to the desired protein concentration.