FUNCTION: β-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The β-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
DISEASE: Polymorphic forms of ADRB2 could impart some form of nocturnal asthma.
SUBUNIT: Binds SLC9A3R1.
PTM: Phosphorylated by PKA and BARK; mediate homologous desensitization of the receptor. PKA-mediated phosphorylation seems to facilitate phosphorylation by BARK
应用类型
WB
免疫原
335-408
来源宿主
鸡
反应性
人
保存建议
ADRB2 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.