FUNCTION: Integrin α-X/β-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
SUBUNIT: Heterodimer of an α and a β subunit. α-X associates with β-2.
SIMILARITY: Contains 1 VWFA domain.
SUBCELLULAR LOCATION: Membrane; single-pass type I membrane protein.
应用类型
WB
免疫原
287-339
来源宿主
鸡
反应性
人
保存建议
ITGAX antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.