FUNCTION: Has aci-reductone dioxygenase (ARD) activity and can function in the 5-methylthioadenosine (MTA) methionine salvage pathway. Down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line.
SUBUNIT: Interacts with MMP14.
SIMILARITY: Belongs to the acireductone dioxygenase (ARD) family.
COFACTOR: Binds 1 nickel ion per monomer. Can also use other divalent metal cations (By similarity).
应用类型
WB
免疫原
1-179
来源宿主
鸡
反应性
人
保存建议
ADI1 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.