FUNCTION: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
DISEASE: Defects in EIF2B2 are a cause of ovarioleukodystrophy [MIM:603896]; also known as vanishing white matter leukodystrophy with ovarian failure. It is a condition of ovarian failure associated with cerebral abnormalities similar to those in patients with vanishing white matter leukodystrophy.
SUBUNIT: Complex of five different subunits; α, β, γ, Δ and ε.
应用类型
WB
免疫原
1-210
来源宿主
鸡
反应性
人, 小鼠
保存建议
EIF2B2 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.